Description
Trauma and uncontrolled bleeding is a major cause of morbidity worldwide. We have developed and structurally characterized potent monoclonal antibodies that control the function and formation of plasmin – a protease that dissolves blood clots and that is dysregulated in the context of life-threatening bleeding. In this project, we will use structural biology and electron microscopy to understand how plasmin functions particularly in the context of its interaction with intact blood clots.
Essential criteria:
Minimum entry requirements can be found here: https://www.monash.edu/admissions/entry-requirements/minimum
Keywords
structural biology, thrombosis, electron microscopy, plasmin, blood clots, bleeding, trauma
School
Biomedicine Discovery Institute (School of Biomedical Sciences) » Biochemistry and Molecular Biology
Available options
PhD/Doctorate
Masters by research
Honours
BMedSc(Hons)
Time commitment
Full-time
Part-time
Top-up scholarship funding available
Yes
Year 1:
$1000
Physical location
Monash Clayton Campus
Research webpage
Co-supervisors
Assoc Prof
Alex de Marco
Prof
Elizabeth Gardiner
(External)